The Role of Physical Activity in the Prevention and Management of Alzheimer’s Disease—Implications for Ontario. Ontario Brain Institute. (2013).
“Approach: To better understand how physical activity can contribute to the prevention and management of Alzheimer’s disease, 871 research articles were reviewed. After closer inspection and quality scoring, 24 randomized control trials and 21 prospective cohort studies examining physical activity and Alzheimer’s disease were selected for further analysis.
“Results: Within older adults with Alzheimer’s disease, regular physical activity improved quality of life (QOL), activities of daily living (ADL), and decreased the occurrence of depression. In older adults without Alzheimer’s disease, those who were very physically active were almost 40% less likely to develop Alzheimer’s disease as those who were inactive. At the population level, it was observed that more than 1 in 7 cases of Alzheimer’s disease could be prevented if everyone who is currently inactive were to become physically active at a level consistent with current activity recommendations. On this basis, potential cost-savings (~$88 to $970 million CDN per year) in healthcare for community-dwelling older adults with Alzheimer’s disease are substantial.” (page 2)